发明名称 |
IDENTIFICATION OF G PROTEIN-COUPLED RECEPTOR LIGANDS AND MODULATORS |
摘要 |
The present invention features methods of assaying for ligands and/or modulators of G protein-coupled receptors, for example, orphan G protein-coupled receptors. The methods of the invention feature constitutively active arrestin mutants, in particular, phosphorylation independent mutants. Also described are specific phosphorylation independent arrestin mutants and methods of making such mutants.
|
申请公布号 |
WO0167106(A3) |
申请公布日期 |
2002.04.11 |
申请号 |
WO2001US07304 |
申请日期 |
2001.03.05 |
申请人 |
MILLENNIUM PHARMACEUTICALS, INC.;BERSTEIN, GABRIEL |
发明人 |
BERSTEIN, GABRIEL |
分类号 |
G01N33/566;(IPC1-7):G01N33/566;C07K14/47 |
主分类号 |
G01N33/566 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|