| 发明名称 |
Pyrazolo[4,3-d]pyrimidinderivater |
| 摘要 |
Compounds of the formula (I): wherein R<SUP>1</SUP>, R<SUP>2</SUP>, R<SUP>4 </SUP>and R<SUP>13 </SUP>are as defined or a pharmaceutically or veterinarily acceptable salt or polymorph thereof, or a pharmaceutically or veterinarily acceptable solvate or pro-drug thereof: are potent and selective inhibitors of type 5 cyclic guanosine 3',5'-monophosphate phosphodiesterase (cGMP PDE5) and have utility in the treatment of, inter alia, male erectile dysfunction (MED) and female sexual dysfunction (FSD). |
| 申请公布号 |
NO20021694(D0) |
申请公布日期 |
2002.04.10 |
| 申请号 |
NO20020001694 |
申请日期 |
2002.04.10 |
| 申请人 |
PFIZER INC |
发明人 |
BUNNAGE, MARK EDWARD;DEVRIES, KEITH MICHAEL;HARRIS, LAURENCE JAMES;LEVETT, PHILIP CHARLES;MATHIAS, JOHN PAUL;NEGRI, JOANNA TERESA;STREET, STEPHEN DEREK ALBERT;WOOD, ALBERT SHAW |
| 分类号 |
C07D231/16;A61K;A61K31/519;A61P;A61P1/00;A61P3/10;A61P9/00;A61P9/04;A61P9/10;A61P9/12;A61P9/14;A61P11/00;A61P11/02;A61P11/06;A61P13/02;A61P13/08;A61P13/10;A61P15/06;A61P15/08;A61P15/10;A61P15/12;A61P17/00;A61P17/06;A61P17/14;A61P25/00;A61P25/02;A61P25/28;A61P27/02;A61P27/06;A61P35/00;A61P35/04;A61P37/08;A61P43/00;C07B61/00;C07D;C07D213/80;C07D213/803;C07D231/38;C07D401/04;C07D401/12;C07D401/14;C07D403/04;C07D487/04;C07F7/18 |
主分类号 |
C07D231/16 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
