发明名称 NOVEL SOLID BODY FORMS OF MESOPROGESTIN 11 beta -[4E-(HYDROXYIMINOMETHYL)-PHENYL]-17 alpha -METHOXYMETHYL-17 beta -METHOXY-ESTRA-4,9-DIEN-3-ONE
摘要 The invention relates to novel solid body forms of mesoprogestin 11 beta -[4E-(hydroxyiminomethyl)-phenyl]-17 alpha -methoxymethyl-17 beta -methoxy-estra-4,9-dien-3-one (oxime J 867), particularly a highly pure and stable amorphous or highly crystalline form (ansolvate/anhydrate) of compound J 867. The invention also relates to methods for producing said novel solid body forms and to the use thereof in pharmaceutical compositions. The novel solid body forms are characterized by exhibiting a high degree of stability. The solid body forms of oxime J 867 can, in particular, be used in the area of fertility control and in hormone replacement therapy.
申请公布号 WO0190137(A3) 申请公布日期 2002.04.04
申请号 WO2001EP05237 申请日期 2001.05.09
申请人 JENAPHARM GMBH & CO. KG;GRAWE, DETLEF;HOESEL, PETER;MUELLER, UWE;WINTER, GABRIELE 发明人 GRAWE, DETLEF;HOESEL, PETER;MUELLER, UWE;WINTER, GABRIELE
分类号 A61K31/569;A61K31/565;A61P5/36;A61P15/08;A61P15/12;A61P15/18;C07J41/00 主分类号 A61K31/569
代理机构 代理人
主权项
地址