发明名称 |
NOVEL SOLID BODY FORMS OF MESOPROGESTIN 11 beta -[4E-(HYDROXYIMINOMETHYL)-PHENYL]-17 alpha -METHOXYMETHYL-17 beta -METHOXY-ESTRA-4,9-DIEN-3-ONE |
摘要 |
The invention relates to novel solid body forms of mesoprogestin 11 beta -[4E-(hydroxyiminomethyl)-phenyl]-17 alpha -methoxymethyl-17 beta -methoxy-estra-4,9-dien-3-one (oxime J 867), particularly a highly pure and stable amorphous or highly crystalline form (ansolvate/anhydrate) of compound J 867. The invention also relates to methods for producing said novel solid body forms and to the use thereof in pharmaceutical compositions. The novel solid body forms are characterized by exhibiting a high degree of stability. The solid body forms of oxime J 867 can, in particular, be used in the area of fertility control and in hormone replacement therapy. |
申请公布号 |
WO0190137(A3) |
申请公布日期 |
2002.04.04 |
申请号 |
WO2001EP05237 |
申请日期 |
2001.05.09 |
申请人 |
JENAPHARM GMBH & CO. KG;GRAWE, DETLEF;HOESEL, PETER;MUELLER, UWE;WINTER, GABRIELE |
发明人 |
GRAWE, DETLEF;HOESEL, PETER;MUELLER, UWE;WINTER, GABRIELE |
分类号 |
A61K31/569;A61K31/565;A61P5/36;A61P15/08;A61P15/12;A61P15/18;C07J41/00 |
主分类号 |
A61K31/569 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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