<p>The invention relates to an immunogenic complex comprising at least one glycoside and at least one lipid, integrated into an iscom complex or matrix, and at least one antigen which antigen is integrated into the iscom complex or coupled on to or mixed with the iscom complex or iscom matrix complex, characterised in that it also comprises at least one enzyme. It also relates to such a complex further comprising at least one peptide which specifically binds to a receptor expressed on a cell capable of antigen presentation, which cell expresses MHC Class I or Class II and to compositions comprising the complexes.</p>
申请公布号
WO0226255(A1)
申请公布日期
2002.04.04
申请号
WO2001SE02117
申请日期
2001.10.01
申请人
ISCONOVA AB;LYCKE, NILS;DALSGAARD, KRISTIAN;MC MOWAT, ALLAN;LOEWENADLER, BJOERN;KAASTRUP, PETER
发明人
LYCKE, NILS;DALSGAARD, KRISTIAN;MC MOWAT, ALLAN;LOEWENADLER, BJOERN;KAASTRUP, PETER