发明名称 |
Method for identifying or screening agonist and antagonist to PPAR |
摘要 |
A method for identifying or screening an agonist for or antagonist to a peroxisome proliferator activated receptor (PPAR) which comprises allowing a test cell and a substance to be tested to coexist, and detecting a change in a ligand-dependent interaction between the PPAR and a coactivator in the test cells due to the substance to be tested by measuring the expression of a reporter gene as an index.
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申请公布号 |
US6365361(B1) |
申请公布日期 |
2002.04.02 |
申请号 |
US20000514247 |
申请日期 |
2000.02.28 |
申请人 |
TANABE SEIYAKU CO., LTD. |
发明人 |
TANIGUCHI TOMOYASU;MIZUKAMI JUNKO |
分类号 |
C12N15/09;C12N1/19;C12Q1/68;C12R1/645;G01N33/566;(IPC1-7):G01N33/53;G01N33/567;G01N33/569;C12Q1/02 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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