发明名称 |
Receptors that regulate cell signaling relating to chemokines |
摘要 |
A method for discovering molecules that regulate cell signaling specific to the dual presence of Duffy antigen receptor for chemokines (DARC) and a chemokine receptor selected from the group consisting of a CXC receptor, a CC receptor and a CXXXC receptor, the method comprising providing a cell that co-expresses DARC and the chemokine receptor; incubating the molecules with the cell; measuring the cell signaling in the cell specific to the dual presence of DARC and the chemokine receptor; and determining whether the cell signaling specific to the dual presence of DARC and the chemokine receptor is regulated by the molecules
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申请公布号 |
US6365356(B1) |
申请公布日期 |
2002.04.02 |
申请号 |
US19990271398 |
申请日期 |
1999.03.17 |
申请人 |
CORNELL RESEARCH FOUNDATION, INC. |
发明人 |
GERSHENGORN MARVIN C. |
分类号 |
C07K14/715;G01N33/68;(IPC1-7):G01N33/53;G01N33/566;C12N5/00 |
主分类号 |
C07K14/715 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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