| 发明名称 |
Substituted imidazoles as dual histamine H<sub>1</sub> and H<sub>3</sub> agonists or antagonists |
| 摘要 |
The present invention discloses novel substituted imidazole compounds which have H3 receptor antagonist activity or dual histamine-H1 and H3 receptor antagonist activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such imidazoles as well as methods of using them to treat allergy, congestion, inflammatory and CNS-related diseases and others. |
| 申请公布号 |
AU9104001(A) |
申请公布日期 |
2002.04.02 |
| 申请号 |
AU20010091040 |
申请日期 |
2001.09.18 |
| 申请人 |
SCHERING CORPORATION |
发明人 |
NENG-YANG SHIH;ROBERT G ASLANIAN;JOHN J. PIWINSKI;ANDREW T. LUPO JR.;ADRIANO AFONSO |
| 分类号 |
A61K31/435;A61P1/00;A61P3/04;A61P9/00;A61P11/00;A61P11/06;A61P25/00;A61P27/16;A61P29/00;A61P37/06;C07D401/12;C07D401/14 |
主分类号 |
A61K31/435 |
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