发明名称 |
PEPTIDE INHIBITORS OF HIV ENTRY |
摘要 |
Described herein are chimeric peptides comprising a soluble trimeric coiled- coil and all or a portion of the N-peptide region of HIV gp41. These molecul es are stable, trimeric coiled-coils that inhibit HIV entry into cells, such as human cells. Such peptides can be further assessed to demonstrate their ability to serve as potent anti-HIV therapeutic molecules and thus, as therapeutic molecules or drugs.
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申请公布号 |
CA2423004(A1) |
申请公布日期 |
2002.03.28 |
申请号 |
CA20012423004 |
申请日期 |
2001.09.21 |
申请人 |
WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH |
发明人 |
KIM, PETER S.;SUNTOKE, TARA R.;ECKERT, DEBRA M. |
分类号 |
A61K48/00;A61K38/00;A61P31/18;C07K14/16;C07K19/00;(IPC1-7):C07K14/155 |
主分类号 |
A61K48/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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