发明名称 |
Process for the preparation of pyrazolo[4,3-d]pyrimidin-7-one compounds and intermediates thereof |
摘要 |
A process is provided for the preparation of compounds of formula (I) herein comprising reacting a compound of formula (II), (III), (IV) or (V) in the presence of -OR3 and a hydroxide trapping agent or in the case of compounds of formula (IV) reacting in the presence of an auxiliary base and a hydroxide trapping agent (i.e. -OR3 is substituted by the auxiliary base), wherein X is a leaving group and R1 to R4 are as defined.
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申请公布号 |
US2002038024(A1) |
申请公布日期 |
2002.03.28 |
申请号 |
US20010916099 |
申请日期 |
2001.07.26 |
申请人 |
ALLERTON CHARLOTTE MOIRA NORFOR;BARBER CHRISTOPHER GORDON;DEVRIES KEITH MICHAEL;HARRIS LAURENCE JAMES;LEVETT PHILIP CHARLES;NEGRI JOANNA TERESA;RAWSON DAVID JAMES;WOOD ALBERT SHAW |
发明人 |
ALLERTON CHARLOTTE MOIRA NORFOR;BARBER CHRISTOPHER GORDON;DEVRIES KEITH MICHAEL;HARRIS LAURENCE JAMES;LEVETT PHILIP CHARLES;NEGRI JOANNA TERESA;RAWSON DAVID JAMES;WOOD ALBERT SHAW |
分类号 |
C07D487/04;(IPC1-7):C07D487/04;A61K31/519 |
主分类号 |
C07D487/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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