| 发明名称 |
GLUTARYL CEPHALOSPORIN AMIDASE FROM PSEUDOMONAS DIMINUTA BS-203 |
| 摘要 |
The invention provides a glutaryl 7-ACA amidase from Pseudomonas diminuta strain BS-203, which catalyzes the hydrolysis of 7-.alpha.-(4- carboxylbutanamido)-cephalosporanic acid to 7-aminocephalosporanic acid and glutaric acid. The invention also provides nucleic acid sequences, vectors, and host cells useful in the production of this amidase. The glutaryl 7-ACA amidase can be used for the preparation of 7-aminocephalosporanic acid.</SDO AB> |
| 申请公布号 |
CA2423161(A1) |
申请公布日期 |
2002.03.28 |
| 申请号 |
CA20012423161 |
申请日期 |
2001.09.19 |
| 申请人 |
BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
BROWN, JOANNE L.;BINDER, ROSS;BURNETT, WILLIAM V., JR.;FRANCESCHINI, THOMAS J.;TONZI, SEAN M.;LIU, SUO WIN;POLITINO, MICHAEL |
| 分类号 |
C12N15/09;C07K14/21;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N9/80;C12N15/31;C12P35/02;C12R1/38 |
主分类号 |
C12N15/09 |
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