IDENTIFICATION OF MODULATORS OF GPR55 ACTIVITY

摘要

A method for identification of an agent that modulates activity of G-protein coupled receptor 55 (GPR 55), which method comprises: (i) contacting a test agent with GPR 55 or a variant thereof which is capable of coupling to a G-protein; and (ii) monitoring for GPR 55 activity in the presence of a G-protein; thereby determining whether the test agent modulates GPR 55 activity.