摘要 |
<p>The invention relates to the hydrazine derivatives represent by the formula (I) (wherein R1 represents hydrogen, optionally substituted C1-C6 alkyl and the like; m represents a integral of 0 to 2, n represents a integral of 0 to 5; A represents a 5-10 membered mono-or poly-cyclic heterocycle containing 1-4 identical or different heteroatoms selected from N, O and S, or a carbocycle; B represents a aromatic ring), the preparation thereof, the compositions containing the compound as active ingredient, the use of the compound for the production of medicaments for the treatment or prevention of myopia, the method for the treatment and prevention of myopia, and a commercial kit containing the compound and related information. The compounds of the invention show effective effects for the treatment or prevention of myopia.</p> |