NEURODEGENERATIVE DISORDER RELATED GENE

摘要

The present invention relates to the use of a polynucleotide fragment comprising PKC gamma gene including type 1 subtype of protein kinase C in the manufacture of a medicament for treating a neurodegenerative disorder. The invention further relates to use of a polypeptide which comprises protein kinase C type 1 in the manufacture of a medicament for treating a neurodegenerative disorder. Further disclosed is a method of testing an animal, such as human, thought to have or be predisposed to having a neurodegenerative disorder which comprises detecting the presence of a mutation in PKC gamma gene and/or its associated promoter.