发明名称 |
4-AMINO-2-UREIDOPYRIMIDINE-5-CARBOXAMIDES, A PROCESS FOR THEPREPARATION THEREOF, PHARMACEUTICALS CONTAINING THESE COMPOUNDS, AND THE USE THEREOF |
摘要 |
4-Amino-2-ureidopyrimidine-5-carboxamides, a process for the preparation thereof, pharmaceuticals containing these compounds, and the use thereof Compounds of the formula I (see formula I) in which R1 to R6 have the stated meanings, and the readily water-soluble salts of these compounds, and a process for the preparation thereof era described. The compounds are suitable for the treatment of lipid meta- bolism disorders which era beneficially influenced by a stimulation of the hepatic LDL receptor. Also described are compounds of the formula II (see formula II) and the salts thereof.
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申请公布号 |
CA2089954(C) |
申请公布日期 |
2002.03.26 |
申请号 |
CA19932089954 |
申请日期 |
1993.02.19 |
申请人 |
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发明人 |
KAMPE, KLAUS-DIETER;GRANZER, ERNOLD;LEINEWEBER, MICHAEL;RACKUR, GERHARD;BOGER, HANS GEORG |
分类号 |
A61K31/505;A61P3/06;C07D233/04;C07D233/30;C07D233/36;C07D233/38;C07D403/04;(IPC1-7):C07D403/04;C07D235/02 |
主分类号 |
A61K31/505 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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