发明名称 Carboxylic acid amides, pharmaceutical compositions containing these compounds and their use
摘要 Carboxylic acid amides of general formulawhich inhibit telomerase and are useful for treating tumour diseases such as carcinomas, sarcomas and leukaemias. Exemplary compounds are:(1) trans-3-(naphth-2-yl)-but-2-enoic acid-N-(2-carboxy-phenyl)-amide, and,(2) trans-3-(naphth-2-yl)-but-2-enoic acid-N-(2-carboxy-4,5-dimethoxy-phenyl)-amide.
申请公布号 US6362210(B1) 申请公布日期 2002.03.26
申请号 US20000618702 申请日期 2000.07.18
申请人 BOEHRINGER INGELHEIM PHARMA KG 发明人 HAUEL NORBERT;PRIEPKE HENNING;DAMM KLAUS;SCHNAPP ANDREAS
分类号 C07D295/10;A61K31/16;A61K31/165;A61K31/167;A61K31/192;A61K31/194;A61K31/36;A61K31/381;A61K31/41;A61K31/415;A61K31/4164;A61K31/4184;A61K31/439;A61K31/44;A61K31/4402;A61K31/4406;A61K31/4409;A61K31/445;A61K31/4453;A61K31/4465;A61K31/47;A61K31/495;A61K31/5375;A61P35/00;A61P43/00;C07C233/46;C07C233/52;C07C233/55;C07C233/63;C07C233/81;C07C235/38;C07C237/30;C07C237/42;C07C237/52;C07C239/20;C07C243/38;C07C255/24;C07C271/20;C07C271/28;C07C275/42;C07C309/51;C07C309/66;C07C311/08;C07C311/13;C07C311/21;C07C311/39;C07C311/46;C07C311/51;C07D207/20;C07D211/16;C07D211/26;C07D213/40;C07D213/53;C07D213/56;C07D213/75;C07D213/79;C07D215/48;C07D215/56;C07D231/12;C07D231/14;C07D231/38;C07D233/26;C07D233/61;C07D233/88;C07D233/90;C07D235/06;C07D235/08;C07D257/04;C07D295/12;C07D295/155;C07D295/192;C07D295/22;C07D307/79;C07D311/06;C07D311/12;C07D317/50;C07D317/68;C07D333/36;C07D333/38;C07D333/40;C07D333/58;C07D333/60;C07D405/04;C07D487/04;(IPC1-7):A61K31/416 主分类号 C07D295/10
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