发明名称 |
Carboxylic acid amides, pharmaceutical compositions containing these compounds and their use |
摘要 |
Carboxylic acid amides of general formulawhich inhibit telomerase and are useful for treating tumour diseases such as carcinomas, sarcomas and leukaemias. Exemplary compounds are:(1) trans-3-(naphth-2-yl)-but-2-enoic acid-N-(2-carboxy-phenyl)-amide, and,(2) trans-3-(naphth-2-yl)-but-2-enoic acid-N-(2-carboxy-4,5-dimethoxy-phenyl)-amide.
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申请公布号 |
US6362210(B1) |
申请公布日期 |
2002.03.26 |
申请号 |
US20000618702 |
申请日期 |
2000.07.18 |
申请人 |
BOEHRINGER INGELHEIM PHARMA KG |
发明人 |
HAUEL NORBERT;PRIEPKE HENNING;DAMM KLAUS;SCHNAPP ANDREAS |
分类号 |
C07D295/10;A61K31/16;A61K31/165;A61K31/167;A61K31/192;A61K31/194;A61K31/36;A61K31/381;A61K31/41;A61K31/415;A61K31/4164;A61K31/4184;A61K31/439;A61K31/44;A61K31/4402;A61K31/4406;A61K31/4409;A61K31/445;A61K31/4453;A61K31/4465;A61K31/47;A61K31/495;A61K31/5375;A61P35/00;A61P43/00;C07C233/46;C07C233/52;C07C233/55;C07C233/63;C07C233/81;C07C235/38;C07C237/30;C07C237/42;C07C237/52;C07C239/20;C07C243/38;C07C255/24;C07C271/20;C07C271/28;C07C275/42;C07C309/51;C07C309/66;C07C311/08;C07C311/13;C07C311/21;C07C311/39;C07C311/46;C07C311/51;C07D207/20;C07D211/16;C07D211/26;C07D213/40;C07D213/53;C07D213/56;C07D213/75;C07D213/79;C07D215/48;C07D215/56;C07D231/12;C07D231/14;C07D231/38;C07D233/26;C07D233/61;C07D233/88;C07D233/90;C07D235/06;C07D235/08;C07D257/04;C07D295/12;C07D295/155;C07D295/192;C07D295/22;C07D307/79;C07D311/06;C07D311/12;C07D317/50;C07D317/68;C07D333/36;C07D333/38;C07D333/40;C07D333/58;C07D333/60;C07D405/04;C07D487/04;(IPC1-7):A61K31/416 |
主分类号 |
C07D295/10 |
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