发明名称 |
NOVEL 8-SUBSTITUTED-2-AMINOTETRALINES |
摘要 |
A compound of formula (I), where Z is hydrogen or halogen, Q is COR1 or 5- or 6-membered aryl which may contain 1 or 2 heteroatoms selected from N, O or S and may be substituted or fused wherein R is hydrogen or C1-methyl (cis- configuration) , R1 is C1-C6 alkyl or an aromatic ring which may contain heteroatoms selected from O and S and may be substituted or fused to an optionally substituted benzene ring, R2 is hydrogen or C1-C6 alkyl and R3 may be different groups defined in claim 1, and enantiomers/salts thereof, processes for preparation of said compounds, pharmaceutical preparations containing said compounds, use of and method of treatment of disorders in CNS by using said compounds.
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申请公布号 |
CA2032498(C) |
申请公布日期 |
2002.03.26 |
申请号 |
CA19902032498 |
申请日期 |
1990.05.23 |
申请人 |
AKTIEBOLAGET ASTRA |
发明人 |
ANDEN, NILS-ERIK;HOOK, BERIT CHRISTINA ELISABET BACKLUND;BJORK, ANNA LENA MARIA;HACKSELL, ULI ALF;HILLVER, SVEN-ERIK;YU, HONG;LIU, YE;MELLIN, EVA CHARLOTTA;PERSSON, EVA MARIE;VALLGARDA, KARL JERK |
分类号 |
C07D209/14;A61K31/135;A61K31/34;A61K31/341;A61K31/343;A61K31/38;A61K31/381;A61K31/395;A61K31/40;A61K31/403;A61K31/404;A61P1/14;A61P9/00;A61P13/02;A61P15/00;A61P25/00;A61P25/04;A61P25/20;A61P25/24;A61P25/26;A61P25/28;C07C;C07C209/68;C07C211/42;C07C215/26;C07C215/34;C07C225/20;C07C229/38;C07C229/50;C07C309/65;C07D211/86;C07D275/06;C07D279/02;C07D279/06;C07D279/12;C07D281/00;C07D281/06;C07D281/18;C07D295/12;C07D307/52;C07D307/81;C07D333/20;C07D521/00;(IPC1-7):C07C225/20 |
主分类号 |
C07D209/14 |
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