发明名称 NOVEL 8-SUBSTITUTED-2-AMINOTETRALINES
摘要 A compound of formula (I), where Z is hydrogen or halogen, Q is COR1 or 5- or 6-membered aryl which may contain 1 or 2 heteroatoms selected from N, O or S and may be substituted or fused wherein R is hydrogen or C1-methyl (cis- configuration) , R1 is C1-C6 alkyl or an aromatic ring which may contain heteroatoms selected from O and S and may be substituted or fused to an optionally substituted benzene ring, R2 is hydrogen or C1-C6 alkyl and R3 may be different groups defined in claim 1, and enantiomers/salts thereof, processes for preparation of said compounds, pharmaceutical preparations containing said compounds, use of and method of treatment of disorders in CNS by using said compounds.
申请公布号 CA2032498(C) 申请公布日期 2002.03.26
申请号 CA19902032498 申请日期 1990.05.23
申请人 AKTIEBOLAGET ASTRA 发明人 ANDEN, NILS-ERIK;HOOK, BERIT CHRISTINA ELISABET BACKLUND;BJORK, ANNA LENA MARIA;HACKSELL, ULI ALF;HILLVER, SVEN-ERIK;YU, HONG;LIU, YE;MELLIN, EVA CHARLOTTA;PERSSON, EVA MARIE;VALLGARDA, KARL JERK
分类号 C07D209/14;A61K31/135;A61K31/34;A61K31/341;A61K31/343;A61K31/38;A61K31/381;A61K31/395;A61K31/40;A61K31/403;A61K31/404;A61P1/14;A61P9/00;A61P13/02;A61P15/00;A61P25/00;A61P25/04;A61P25/20;A61P25/24;A61P25/26;A61P25/28;C07C;C07C209/68;C07C211/42;C07C215/26;C07C215/34;C07C225/20;C07C229/38;C07C229/50;C07C309/65;C07D211/86;C07D275/06;C07D279/02;C07D279/06;C07D279/12;C07D281/00;C07D281/06;C07D281/18;C07D295/12;C07D307/52;C07D307/81;C07D333/20;C07D521/00;(IPC1-7):C07C225/20 主分类号 C07D209/14
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