MUTEINS OF THE CGRP 1-7 PEPTIDE FRAGMENT AND USE THEREOF AS NICOTINIC NEURONAL RECEPTOR ENHANCERS

摘要

Muteins of the Ser-Cys-Asn-Thr-Ala-Thr-Cys sequence from the N-terminal 1-7 fragment of the CGRP peptide, possessing an enhancing action on the activation of neuronal nicotinic receptors, their pharmaceutical compositions containing the same and their use for the potential therapy of neurological diseases are described.