| 摘要 |
An adsorbent for reducing the concentration of fibrinogen and/or fibrin in blood or blood plasma comprises a matrix and synthetic lateral chains that are covalently bonded to the matrix. The matrix can, in principle, consist of any arbitrary carriers; however, it exhibits, preferably, porous, unaggregated, spherical particles in a range of particle sizes from 50 to 250 mum, which possess an exclusionary threshold of at least 107 Daltons. The lateral chains possess at least two amino groups whose nitrogen atoms in the chain are at least 2.6 Angstroms removed from one another, and they exhibit no peptides or aromatic groups of any kind. The at least two amino groups are preferably separated from one another by 4 to 6 carbon atoms. An adsorber for the purpose of reducing the concentration of fibrinogen and/or fibrin in blood or blood plasma may be produced from the adsorbent.
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