T-BUTOXYCARBONYLAMINOETHYLAMINE FOR THE SYNTHESIS OF PNA MONOMER UNITS, AMINO ACID DERIVATIVES, INTERMEDIATES THEREOF, AND PROCESSES FOR PRODUCTIONS OF THEM

摘要

The invention aims at providing processes for the production of amino acid derivatives of the general formula (I) and t-butoxycarbonylaminoethylamine being an intermediate for the production of the derivatives (I), which can attain high yield without troublesome operation and are easily applicable to mass production; novel amino acid derivatives of the general formula (IV) and intermediates for the synthesis of the same; and processes for the production of the derivatives (IV) and the intermediates. That is, the invention relates to a process for the production of amino acid derivatives of the general formula (I) which comprises the step of hydrolyzing an alkyl ester of an amino acid derivative (I); amino acid derivatives of the general formula (IV); and a process for the production of amino acid derivatives (IV), characterized by comprising the step of reducing a benzyloxycarbonyl-<-amino acid derivative. (IV) In the formulae, R?1> is hydrogen or C1-5 alkyl; and R<2> is C1-4 alkyl.