| 摘要 |
The present invention relates to trimesic acid amides, pharmaceutical compositions comprising said compounds, uses of said compounds and compositions, and processes for their preparation. Specifically, this invention relates to means to enhance insulin-dependent glucose uptake. More specifically, the invention concerns compounds and pharmaceutical compositio ns that active the insulin receptor kinase, which leads to an increased sensitivity to insulin and an increase in glucose uptake, as well as process es for preparation of the compounds. As such, the invention also concerns metho ds or uses of the compounds for the treatment of animals with hyperglycemia, especially for the treatment of type 2 diabetes. |
