| 发明名称 |
METHOD OF MONITORING THE EFFECT OF CATHEPSIN S INHIBITORS |
| 摘要 |
The present invention relates to a method for monitoring the effect of in vivo administration of Cathepsin S inhibitors by measuring accumulation of an intermediate degradation product of invariant chain (Ii), in particular the p10 Ii fragment, in blood of dosed patients. |
| 申请公布号 |
WO0221129(A1) |
申请公布日期 |
2002.03.14 |
| 申请号 |
WO2001US26373 |
申请日期 |
2001.08.24 |
| 申请人 |
ORTHO-MCNEIL PHARMACEUTICAL, INC. |
发明人 |
THURMOND, ROBIN;SUN, SIQUAN;KARLSSON, LARS |
| 分类号 |
G01N33/53;C12Q1/37;G01N33/573;(IPC1-7):G01N33/535;G01N33/545 |
主分类号 |
G01N33/53 |
| 代理机构 |
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| 主权项 |
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