发明名称 |
Novel anti-estrogenic steroids, and associated pharmaceutical compositions and methods of use |
摘要 |
Novel anti-estrogenic compounds are provided which are useful to treat a variety of disorders, particularly estrogen-dependent disorders. Preferred compounds have a 1,3,5-estratriene nucleus, and are substituted at the C-17 or C-11 position with a molecular moiety which renders the compounds effective to competitively block the binding of estrogen to its receptor. Particularly preferred compounds are 17-desoxy-1,3,5-estratrienes. Therapeutic methods and pharmaceutical compositions are provided as well.
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申请公布号 |
US2002032180(A1) |
申请公布日期 |
2002.03.14 |
申请号 |
US20010872825 |
申请日期 |
2001.05.31 |
申请人 |
TANABE MASATO;PETERS RICHARD H.;CHAO WAN-RU;JONG LING |
发明人 |
TANABE MASATO;PETERS RICHARD H.;CHAO WAN-RU;JONG LING |
分类号 |
A61K9/02;C07J41/00;C07J43/00;(IPC1-7):A61K31/56;C07J53/00 |
主分类号 |
A61K9/02 |
代理机构 |
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