发明名称 PIPERIDINE DERIVATIVES FOR USE 2,3-OXIDOSQUALENE-LANOSTEROL CYCLASE INHIBITORS
摘要 The present invention relates to compound of formula (I), wherein U, V, W, A<1>, A<2>, A<3>, A<4>, A<5>, m and n are as defined in the description and claims and pharmaceutically acceptable salts and/or pharmaceutically acceptable esters thereof. The compounds are useful for the treatment and/or prophylaxis of diseases which are associated with 2,3-oxidosqualene-lanosterol cyclase such as hypercholesterolemia, hyperlipemia, arteriosclerosis, vascular diseases, mycoses, gallstones, tumors and/or hyperproliferative disorders, and treatment and/or prophylaxis of impaired glucose tolerance and diabetes.
申请公布号 WO0220483(A1) 申请公布日期 2002.03.14
申请号 WO2001EP09941 申请日期 2001.08.29
申请人 F. HOFFMANN-LA ROCHE AG 发明人 ACKERMANN, JEAN;AEBI, JOHANNES;CHUCHOLOWSKI, ALEXANDER;DEHMLOW, HENRIETTA;MORAND, OLIVIER;WALLABAUM, SABINE;WELLER, THOMAS
分类号 A61K31/445;A61K31/4523;A61K31/4525;A61K31/454;A61K31/4545;A61K31/496;A61K31/55;A61P1/16;A61P3/06;A61P3/10;A61P9/00;A61P9/10;A61P31/10;A61P33/00;A61P35/00;A61P43/00;C07D211/18;C07D211/22;C07D211/26;C07D211/44;C07D211/46;C07D211/96;C07D401/12;C07D405/12;C07D417/12;(IPC1-7):C07D211/44 主分类号 A61K31/445
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