摘要 |
A rapid, quantitative assay for detection of an immune response factor to a preselected micro-organism (especially a virus such as HIV), produced by an <I>in vitro</I> cell culture exposed to said microorganism, comprises detection of the suppression of replication of said microorganism. The cell line used in the assay may produce a reporter analyte, such as an enzyme (particularly b -galactosidase) or a nucleic acid, indicative of such suppression and the immune response factor detected may be a cytokine, chemokine, antibody or, particularly, a CD8+ cell antiviral factor (CAF). |