发明名称 Benzothiepin derivatives, process for the preparation of the same and uses thereof
摘要 The invention provides compounds of the formula:wherein the ring A is an optionally substituted benzene ring; R1 is an optionally substituted non-aromatic heterocyclic group; R2 and R3 are independently hydrogen atom or an optionally substituted hydrocarbon group; n is an integer of 0-3; or salts thereof, which are useful as medicines having an osteogenesis promoting effect and chondrogensis promoting effect.The present invention relates to an amine compound having an excellent effect of inhibiting production and/or secretion of amyloid-b protein, a production and use thereof. Especially, it is effective for preventing and/or treating, for example, neurodegenerative diseases, amyloid angiopathy, neurological disorders caused by cerebrovascular disorders, and so forth.
申请公布号 US6355672(B1) 申请公布日期 2002.03.12
申请号 US20010744857 申请日期 2001.01.30
申请人 TAKEDA CHEMICAL INDUSTRIES, LTD. 发明人 YASUMA TSUNEO;MAKINO HARUHIKO;MORI AKIRA
分类号 A61P19/08;C07D211/88;C07D233/74;C07D263/44;C07D277/04;C07D295/135;C07D495/04;(IPC1-7):C07D337/08;A61K31/38 主分类号 A61P19/08
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