发明名称 Biphenylderivate
摘要 The invention relates to novel biphenyl derivatives of the general formula (I), wherein R<4> represents an aromatic heterocycle, and to the physiologically acceptable salts or solvates thereof. The inventive compounds are integrin inhibitors and are used for combating thromboses, cardiac infarction, coronary heart diseases, arteriosclerosis, inflammations, tumors, osteoporosis, infections and restenosis following angioplasty or for pathological processes that are maintained or propagated by angiogenesis.
申请公布号 DE10041423(A1) 申请公布日期 2002.03.07
申请号 DE20001041423 申请日期 2000.08.23
申请人 MERCK PATENT GMBH 发明人 STAEHLE, WOLFGANG;GOODMAN, SIMON;HOELZEMANN, GERHARD
分类号 A61K31/4168;A61K31/4184;A61P3/10;A61P7/02;A61P9/00;A61P9/10;A61P17/02;A61P19/02;A61P19/10;A61P27/02;A61P29/00;A61P31/00;A61P35/00;A61P41/00;A61P43/00;C07D233/48;C07D233/88;C07D235/30;(IPC1-7):C07K5/02;A61K38/04 主分类号 A61K31/4168
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