| 发明名称 |
ANTIBODIES AGAINST HUMAN CD40 |
| 摘要 |
<p>The Applicants have discovered a novel antibody, more specifically a chimerized anti-human CD40 monoclonal antibody, which blocks the interaction between gp39 and CD40. The anti-CD40 antibodies of the present invention are effective in modulating humoral immune responses against T cell-dependent antigens, collagen induced arthritis, and skin transplantation, and are also useful for their anti-inflammatory properties.</p> |
| 申请公布号 |
SK12092000(A3) |
申请公布日期 |
2002.03.05 |
| 申请号 |
SK20000001209 |
申请日期 |
1999.02.10 |
| 申请人 |
BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
ARUFFO ALEJANDRO A.;HOLLENBAUGH DIANE;SIADAK ANTHONY W.;BERRY KAREN K.;HARRIS LINDA J.;THORNE BARBARA A.;BAJORATH JURGEN;WU HERREN;HUSE WILLIAM D.;WATKINS JEFFRY D. |
| 分类号 |
C12N15/09;A61K38/00;A61K39/395;A61P19/02;A61P29/00;A61P37/02;A61P37/06;A61P43/00;C07K14/46;C07K14/725;C07K16/28;C12N1/21;C12N15/13;(IPC1-7):A61K39/395 |
主分类号 |
C12N15/09 |
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