摘要 |
1H-Imidazopyridine derivatives of the general formula (1) or salts thereof, useful in the prevention and/or treatment of cytokine-mediated diseases: (1) wherein R<1> is hydrogen, alkyl, cycloalkyl, or aryl; R<2> is hydrogen or lower alkyl; R<3> is a saturated nitrogenous heterocyclic group; m is an integer of 0 to 3; and A is a ring represented by the general formula (2) or (3): (2) or (3) (wherein X is sulfur or CH=CH; and R<4>, R<5>, R<6> and R<7> are each independently hydrogen, halogeno, alkyl, alkoxy, amino, alkanesulfonyl, or arylsulfonyl, with the proviso that when X is CH=CH, R<4> is hydrogen and R<5 >is a group exclusive of hydrogen). |