| 发明名称 |
PHARMACEUTICAL COMPOSITIONS COMPRISING A MODULATOR OF ADAMTS-1 |
| 摘要 |
The present invention is based on the discovery that the metalloproteinase, ADAMTS-1 (A Disintegrin And Metalloproteinase), is associated with obesity, atherosclerosis, insulin resistance syndrome and non-insulin dependent diabetes. The application is directed to methods for screening for specidic modulators of ADAMS-1 activity, and the use of said modulators for treating the above-mentioned diseases.
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| 申请公布号 |
WO0216632(A1) |
申请公布日期 |
2002.02.28 |
| 申请号 |
WO2001GB03650 |
申请日期 |
2001.08.16 |
| 申请人 |
ASTRAZENECA AB;ASTRAZENECA UK LIMITED;BRODIN, PETER;THELIN, ANDERS |
发明人 |
BRODIN, PETER;THELIN, ANDERS |
| 分类号 |
G01N33/50;A61K38/00;A61K45/00;A61P3/04;A61P3/10;A61P9/10;A61P43/00;C12N15/09;C12Q1/02;C12Q1/37;C12Q1/68;G01N33/15;G01N33/573;(IPC1-7):C12Q1/00 |
主分类号 |
G01N33/50 |
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