| 摘要 |
The invention provides an infusion cannula modified to incorporate one or more medicinal agents. The infusion cannula comprises a tube having an inner lumen and an external surface. The tube comprises a flexible, biologically compatible elastomeric material and a coating adhered to the external surface of the tube, wherein the coating comprises a medicinal agent in a polymer matrix. In a preferred embodiment, the polymer is capable of sustained release of the medicinal agent. The invention additionally provides a method for producing an infusion cannula. The method comprises coating a tube with a medicinal agent in a polymer matrix, wherein the tube comprises a flexible, biologically compatible elastomeric material. In some embodiments, the coating comprises dipping the tube into the polymer matrix, or spraying or painting the polymer matrix onto the tube. The invention thus provides and infusion cannula produced by the above method.
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