DMS:ACCEPTOR OXIDOREDUCTASE

摘要

A recombinant bacterial DMS:acceptor oxidoreductase, subunit amino acid sequences andencoding nucleic acids are provided. The DMS:acceptor oxidoreductase is enantioselective with respect to prochiral organic sulfoxide substrates. The DMS:acceptor oxidoreductase is useful in methods of oxidizing prochiral organic sulfides to form corresponding sulfoxides, and more particularly, to form sulfoxide (S) enantiomers which may be used in the synthesis of chiral drugs.