| 摘要 |
A coating composition, in both its uncrosslinked and crosslinked forms, for use in delivering a medicament from the surface of a medical device position ed in vivo. Once crosslinked, the coating composition provides a gel matrix adapted to contain the medicament in a form that permits the medicament to b e released from the matrix in a prolonged, controlled, predictable and effecti ve manner in vivo. A composition includes a polyether monomer, such as an alkox y poly(alkylene glycol), a carboxylic acid-containing monomer, such as (meth)acrylic acid, a photoderivatized monomer, and a hydrophilic monomer su ch as acrylamide.
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