摘要 |
<p>2-Aminopyridine compounds of the general formula (I) and salts thereof, exhibiting excellent adenosine receptor (A1, A2a, or A2b receptor) antagonism wherein R1 is cyano, carboxyl, or optionally substituted carbamoyl; R2 is hydrogen, hydroxyl, optionally substituted C¿1-6? alkoxy, an optionally substituted C6-14 aromatic carbocyclic group, or an optionally substituted 5- to 14-membered aromatic heterocyclic group; and R?3 and R4¿ are each independently an optionally substituted C¿6-14? aromatic carbocyclic group, a 5- to 14-membered nonaromatic heterocyclic group, a 5- to 14-membered aromatic heterocyclic group, or the like.</p> |