发明名称 AMORPHOUS (QUINOLIN-2-YLMETHOXY) INDOLES
摘要 A form of 3-[N-(p-chlorobenzyl)-3- (t-butylthio)-5-(quinolin-2-ylmethoxy)indol-2-yl]- 2,2-dimethylpropanoic acid sodium salt, obtained by freeze or spray drying, is more soluble in water than the crystalline form thereof. The compound is useful as an anti-asthmatic, anti-allergic, anti-inflam- matory, or cytoprotective agent. It is also useful in treating; diarrhea, hypertension, angina, platelet aggregation, cerebral spasm, premature labor, spontaneous abortion, dysmenorrhea, and migraine.
申请公布号 CA2082568(C) 申请公布日期 2002.02.19
申请号 CA19922082568 申请日期 1992.11.10
申请人 MERCK FROSST CANADA & CO. 发明人 HUTCHINSON, JOHN H.;DOWN, BRIAN
分类号 A61K31/47;A61P11/00;A61P43/00;C07D401/12;(IPC1-7):C07D401/12 主分类号 A61K31/47
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