A novel polypeptide-nadp dependent leukotriene b412-hydroxydehydrogenase-36 and the polynucleotide encoding said polypeptide

摘要

The invention disclosed a new kind of NADP-dependent leukotriene B412-hydroxydehydrogenase-36 and the polynucleotide encoding said polypeptide and a process for producing the polypeptide by recombinant methods. It also disclosed the method of applying the polypeptide for the treatment of various kinds of diseases, such as inflammation and oxygen radical damage disease. The antagonist of the polypeptide and therapeutic use of the same is also disclosed. In addition, it refers to the use of polynucleotide encoding said NADP-dependent leukotriene B412-hydroxydrogenase-36.