| 发明名称 |
An improved method for processing activated protein c with reduced auto-degradation |
| 摘要 |
<p>The present invention relates to pharmaceutical formulations of activated protein C which also comprises sucrose, sodium chloride and sodium citrate buffer at a pH between about 5.5 and about 6.5. The activated protein C formulations of the present invention are more stable than other formulations of activated protein C and demonstrate fewer degradation products over time.</p> |
| 申请公布号 |
IN187157(B) |
申请公布日期 |
2002.02.16 |
| 申请号 |
IN1998CA75219 |
申请日期 |
1998.04.27 |
| 申请人 |
ELI LILLY AND COMPANY |
发明人 |
CARLSON ANDREW DAVID;SHELIGA THEODORE ARSAY;BAKER JEFFREY CLAYTON;HUANG LIHUA |
| 分类号 |
A61K38/46;A61K31/715;A61K38/16;A61K38/48;A61K47/26;A61P7/02;A61P9/00;A61P9/10;A61P9/14;A61P43/00;C07K1/14;C12N9/64;(IPC1-7):C07K3/12 |
主分类号 |
A61K38/46 |
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