| 发明名称 |
USE OF 3-O-DEACYLATED MONOPHOSPHORYL LIPID A OR MONOPHOSPHORYL LIPID A IN COMBINATION WITH GM-CSF OR IL-12 AS ADJUVANT COMBINATION IN ANTIGENIC COMPOSITION FOR ENHANCING IMMUNE RESPONSE IN VERTEBRATE |
| 摘要 |
The use of 3-O-deacylated monophosphoryl lipid A or monophosphoryl lipid A and derivatives and analogs thereof, in combination with a cytokine or lymphokine such as granulocyte macrophage colony stimulating factor or interleukin-12 is useful as an adjuvant combination in an antigenic composition to enhance the immune response in a vertebrate host to a selected antigen. |
| 申请公布号 |
UA76406(C2) |
申请公布日期 |
2002.02.15 |
| 申请号 |
UA20010128558 |
申请日期 |
2000.05.12 |
| 申请人 |
WHITE HOLDINGS CORPORATION |
发明人 |
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| 分类号 |
A61K9/107;A61K35/12;A61K38/00;A61K38/17;A61K38/20;A61K39/00;A61K39/002;A61K39/02;A61K39/095;A61K39/12;A61K39/155;A61K39/21;A61K39/35;A61K39/39;A61P25/28;A61P31/04;A61P31/12;A61P31/16;A61P31/20;A61P35/00;A61P37/04;C07K14/52;C07K14/535;C07K14/54;C07K19/00 |
主分类号 |
A61K9/107 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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