| 发明名称 |
HETEROCYCLIC COMPOUNDS AS LIGANDS OF THE GABAA RECEPTOR |
| 摘要 |
Disclosed are heterocyclic compounds of the formula and the pharmaceutically acceptable salts thereof wherein the variables A, V, Y, J, E, X, G, Q, W, Z, b, n and m are defined herein. These compounds are highly selective agonists , antagonists or inverse agonists for GABAA brain receptors or prodrugs of agonists, antagonists or inverse agonists for GABAA brain receptor.
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| 申请公布号 |
CA2420967(A1) |
申请公布日期 |
2002.02.14 |
| 申请号 |
CA20012420967 |
申请日期 |
2001.08.06 |
| 申请人 |
NEUROGEN CORPORATION;PFIZER, INC. |
发明人 |
LUKE, GEORGE P.;NAGEL, ART ADAM;LIU, XIAOJUN;VINCENT, LAWRENCE ALBERT;WANG, ZHE-QING;CURRIE, KEVIN S.;GHOSH, MANUKA;LEE, KYUNGAE;YUAN, JUN;YOHANNES, DANIEL;MAYNARD, GEORGE;XIE, LINGHONG |
| 分类号 |
A61K31/4162;A61K31/4178;A61K31/4188;A61K31/429;A61K31/437;A61K31/4375;A61K31/444;A61K31/4709;A61K31/4745;A61K31/497;A61K31/506;A61K31/519;A61K31/5377;A61P25/00;A61P25/20;A61P25/22;A61P25/24;A61P25/28;A61P43/00;C07D403/04;C07D471/04;C07D471/14;C07D487/04;C07D487/14;C07D498/04;C07D513/04;(IPC1-7):C07D491/14 |
主分类号 |
A61K31/4162 |
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