| 摘要 |
<p>Inflammatory cytokine production inhibitors, IL-10 production promoters or apoptosis inhibitors containing as the active ingredient compounds relating to nicotinic acid. The compounds relating to nicotinic acid usable herein include nicotinic acid, nicotinamide, 1-methyl-2-pyridone-5-carboxamide, 1-methyl-2-pyridone and tryptophan. These drugs are useful in inhibiting the production of inflammatory cytokines such as IL-12, IFN-η or TNF-a. It is also possible to use these drugs for promoting the production of IL-10 which is an anti-inflammatory cytokine. Use of these drugs in treating hepatitis, etc.</p> |
