| 发明名称 |
4-heterocyclysulfonamidyl-6-methoxy-5-(2-methoxy-phenoxy)-2-pyridyl-pyrimidine derivatives, process of their preparation and use as endothelin receptor |
| 摘要 |
<p>The compounds of formula (I)wherein R1 has the significance as given in the description, are inhibitors of endothelin receptors and can therefore be used for the treatment of disorders which are associated with abnormal vascular tone and endothelial dysfunction.</p> |
| 申请公布号 |
CZ20013108(A3) |
申请公布日期 |
2002.02.13 |
| 申请号 |
CZ20010003108 |
申请日期 |
2000.02.28 |
| 申请人 |
F. HOFFMANN-LA ROCHE AG |
发明人 |
BREU VOLKER;COASSOLO PHILIPPE;NEIDHART WERNER;ROUX SEBASTIEN;WEISS PETER |
| 分类号 |
A61K31/505;A61P9/00;C07D401/14;C07D417/14;(IPC1-7):C07D401/14;A61P13/00;A61P11/00;A61K31/506;A61P1/04 |
主分类号 |
A61K31/505 |
| 代理机构 |
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