发明名称 |
Process for preparing antifungal V-28-3M |
摘要 |
An industrially suitable process for preparing V-28-3M useful as an antimycotic agent by conducting methyl esterification of V-28-3 efficiently. V-28-2 is efficiently converted into V-28-3M by protecting the amino group of the amino sugar of V-28-3 with an appropriate protecting group, subjecting the carboxyl group of V-28-3 to methyl esterification with methyl methanesulfonate or methyl p-toluenesulfonate in the presence of a base, and deprotecting the N-protected intermediate.
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申请公布号 |
US6346610(B1) |
申请公布日期 |
2002.02.12 |
申请号 |
US19990445240 |
申请日期 |
1999.12.03 |
申请人 |
AJINOMOTO CO., LTD. |
发明人 |
KATAOKA NORIYASU;TANAKA KENZO;YATAGAI MASANOBU |
分类号 |
C07H17/08;(IPC1-7):C07M1/00 |
主分类号 |
C07H17/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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