发明名称 |
Use of bicyclic pyrimidine derivatives with the other ring being a heteroaryl as medicaments; pyridopyrimidine compounds |
摘要 |
4-substituted amino pyrido pyrimidine and 4-substituted amino pyrido pyrimidine inhibitors of the epidermal growth factor receptor family of tyrosine kinase are described in addition to pharmaceutical compositions of the same. They are useful in treating proliferative diseases such as cancer, synovial pannus invasion in arthritis, psoriasis, vascular restenosis and angiogenesis and also useful in the treatment of pancreatitis and kidney disease and in use as a contraceptive agent.
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申请公布号 |
NZ281011(A) |
申请公布日期 |
2002.02.01 |
申请号 |
NZ19950281011 |
申请日期 |
1995.01.23 |
申请人 |
WARNER-LAMBERT COMPANY |
发明人 |
BRIDGES, ALEXANDER JAMES;DENNY, WILLIAM ALEXANDER;FRY, DAVID;KRAKER, ALAN;MEYER, ROBERT FREDERICK;REWCASTLE, GORDON WILLIAM;THOMPSON, ANDREW MARK |
分类号 |
C07D487/04;A61K31/495;A61K31/4985;A61K31/505;A61K31/519;A61K31/525;A61P1/00;A61P13/02;A61P15/00;A61P17/00;A61P29/00;A61P35/00;A61P43/00;C07D239/00;C07D471/04;C07D471/14;C07D473/34;C07D487/02;C07D491/048;C07D495/04;C07D498/04;C07D513/04;(IPC1-7):C07D487/04 |
主分类号 |
C07D487/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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