发明名称 |
METHOD OF PREPARING A SOMATIC CELLS FOR NUCLEAR TRANSFER |
摘要 |
The production of genetically modified animals, in which the genetic modifications are engineered in somatic cells cultured in vitro by gene targeting, is described. Genetically modified cells may then used as nuclear donors to produce, inter alia, live animals. The methods described can also be used to validate loci in animal chromosomes which are suitable sites for transgene addition to cells.
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申请公布号 |
US2002012660(A1) |
申请公布日期 |
2002.01.31 |
申请号 |
US19990475674 |
申请日期 |
1999.12.30 |
申请人 |
COLMAN ALAN;SCHNICKE ANGELIKA E.;KIND ALEXANDER J.;AYARES DAVID L.;DAI YIFAN |
发明人 |
COLMAN ALAN;SCHNICKE ANGELIKA E.;KIND ALEXANDER J.;AYARES DAVID L.;DAI YIFAN |
分类号 |
A01K67/027;A61K48/00;C12N15/10;C12N15/90;H04L12/24;(IPC1-7):A01K67/027 |
主分类号 |
A01K67/027 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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