| 发明名称 |
NAPHTHALENE DERIVATIVES AS PROSTAGLANDIN I2 AGONISTS |
| 摘要 |
<p>A compound or the formula: <IMAGE> wherein R1 is carboxy or protected carboxy, R2 is hydrogen, hydroxy or protected hydroxy, R3 is hydrogen, hydroxy, protected hydroxy, etc., R4 is hydrogen or halogen, A1 is lower alkylene, A2 is bond or lower alkylene, -R5 is <IMAGE> (in which R6 is mono(or di or tri)aryl(lower)alkyl and Z is N or CH), etc., and <IMAGE> etc., and a pharmaceutically acceptable salt thereof which are useful as medicaments.</p> |
| 申请公布号 |
GR3037080(T3) |
申请公布日期 |
2002.01.31 |
| 申请号 |
GR20010401952T |
申请日期 |
2001.10.31 |
| 申请人 |
FUJISAWA PHARMACEUTICAL CO., LTD. |
发明人 |
TANIGUCHI, KIYOSHI;NAGANO, MASANOBU;HATTORI, KOUJI;TSUBAKI, KAZUNORI;OKITSU, OSAMU;TABUCHI, SEIICHIRO |
| 分类号 |
A61K31/16;A61K31/335;A61K31/336;A61K31/44;A61K31/4418;A61K31/4425;A61K31/50;A61P7/02;A61P9/10;A61P9/12;A61P43/00;C07C69/145;C07C235/40;C07C271/10;C07C271/12;C07C271/24;C07C271/28;C07C271/32;C07C281/02;C07D213/64;C07D237/14;C07D303/12;C07D303/16;(IPC1-7):C07D213/64 |
主分类号 |
A61K31/16 |
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