发明名称 |
Presentation of hydrophobic antigens to T-cells by CD1 molecules |
摘要 |
Provided are CD-1 presented antigens, compositions, cells, inhibitors and methods relating to the use of hydrophobic antigen presentation by CD1 molecules, including: methods for detecting the presence of a CD1-presented hydrophobic antigen in a sample; methods for isolating such CD1-presented antigens and the isolated antigens; vaccines containing CD1-presented antigens and vaccination methods; methods of blocking CD1 antigen presentation; methods of identifying and/or isolating CD1 blocking agents and the isolated CD1 blocking agents; methods of inducing CD1 expression; and T-cells for use in the methods disclosed herein.
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申请公布号 |
US2002009465(A1) |
申请公布日期 |
2002.01.24 |
申请号 |
US20010861963 |
申请日期 |
2001.05.21 |
申请人 |
PORCELLI STEVEN A.;BRENNER MICHAEL B.;BECKMAN EVAN M.;FURLONG STEPHEN T. |
发明人 |
PORCELLI STEVEN A.;BRENNER MICHAEL B.;BECKMAN EVAN M.;FURLONG STEPHEN T. |
分类号 |
A61K39/00;A61K39/04;C07K14/74;C07K16/28;C12P19/04;(IPC1-7):A61K39/04;C12N5/08 |
主分类号 |
A61K39/00 |
代理机构 |
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代理人 |
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主权项 |
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