发明名称 |
APOPTOSIS-ASSOCIATED GENE |
摘要 |
<p>A polypeptide possessing an action of causing chromatin condensation; a sense nucleic acid encoding the polypeptide; an antisense nucleic acid thereof; a probe or primer capable of specifically binding to the nucleic acid; an antibody or a fragment thereof against the polypeptide; an agent for controlling apoptosis, comprising the nucleic acid, the polypeptide, or the antibody or a fragment thereof; a screening method for a substance for controlling chromatin condensation, comprising evaluating an activity of causing chromatin condensation exhibited by the polypeptide; and a substance for controlling chromatin condensation. The present invention is useful for screening a substance controlling apoptosis, its use for controlling apoptosis and its applications to various diseases accompanying apoptosis.</p> |
申请公布号 |
EP1174504(A1) |
申请公布日期 |
2002.01.23 |
申请号 |
EP20000915397 |
申请日期 |
2000.04.07 |
申请人 |
SHIONOGI & CO., LTD. |
发明人 |
SAHARA, SETSUKO;EGUCHI, YUTAKA;TSUJIMOTO, YOSHIHIDE |
分类号 |
A61K38/00;A61P25/00;A61P43/00;C07K14/47;C12N15/12;(IPC1-7):C12N15/12;C07K14/435;C12Q1/68;A61K39/395;C07K16/18 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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