发明名称 |
Genomics via optical mapping with ordered restriction maps |
摘要 |
A method of producing high-resolution, high-accuracy ordered restriction maps based on data created from the images of populations of individual DNA molecules (clones) digested by restriction enzymes. Detailed modeling and a statistical algorithm, along with an interactive algorithm based on dynamic programming and a heuristic method employing branch-and-bound procedures, are used to find the most likely true restriction map, based on experimental data.
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申请公布号 |
US6340567(B1) |
申请公布日期 |
2002.01.22 |
申请号 |
US20000678002 |
申请日期 |
2000.10.03 |
申请人 |
WISCONSIN ALUMNI RESEARCH FOUNDATION |
发明人 |
SCHWARTZ DAVID C.;MISHRA BHUBANESWAR;ANANTHARAMAN THOMAS S. |
分类号 |
C12Q1/68;G06F19/00;(IPC1-7):C12Q1/00;C12P21/06;C12P1/00;G01N21/00 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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