发明名称 |
N-[4-(3-chloro-4-fluoro-phenylamino)-7-(3-morpholin-4-yl-propoxy)-quinazolin-6-yl]-acrylamide, irreversible inhibitor of tyrosine kinases |
摘要 |
<p>This invention relates to the compound N-[4-(3-chloro4-fluoro-phenylamino)-7-(3-morpholin-4-yl-propoxy)-quinazolin-6-yl]-acrylamide that is an irreversible inhibitor of tyrosine kinases. This invention also relates to a method of treating cancer, atherosclerosis, restenosis, endometriosis, and psoriasis using the compound N-[4-(3-chloro4-fluoro-phenylamino)-7-(3-morpholin4-yl-propoxy)-quinazolin-6-yl]-acrylamide, and to a pharmaceutical composition that comprises the compound N-[4-(3-chloro4-fluoro-phenylamino)-7-(3-morpholin-4-yl-propoxy)-quinazolin-6-yl]-acrylamide.</p> |
申请公布号 |
CZ20011759(A3) |
申请公布日期 |
2002.01.16 |
申请号 |
CZ20010001759 |
申请日期 |
1999.09.23 |
申请人 |
WARNER-LAMBERT COMPANY |
发明人 |
BRIDGES ALEXANDER JAMES;DRISCOLL DENISE;KLOHS WAYNE DANIEL |
分类号 |
A61K31/5377;A61P9/10;A61P15/00;A61P17/06;A61P19/10;A61P27/02;A61P29/00;A61P35/00;A61P43/00;C07D239/94;(IPC1-7):C07D413/12;A61K31/517 |
主分类号 |
A61K31/5377 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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