发明名称 |
PROCESS FOR THE PREPARATION OF SUBSTITUTED OCTANOYL AMIDES |
摘要 |
Compounds of formula (II) are simultaneously halogenated in the 5 position and hydroxylated in the 4 position under lactonization, the halolactone is converted into a hydroxylactone and then the hydroxy group into a leaving group, the leaving group is replaced with azide, the lactone amidated and then the azide converted to the amine group, in order to obtain compounds of formula (I). |
申请公布号 |
WO0202508(A1) |
申请公布日期 |
2002.01.10 |
申请号 |
WO2001CH00399 |
申请日期 |
2001.06.26 |
申请人 |
SPEEDEL PHARMA AG;HEROLD, PETER;STUTZ, STEFAN;SPINDLER, FELIX |
发明人 |
HEROLD, PETER;STUTZ, STEFAN;SPINDLER, FELIX |
分类号 |
C07B61/00;C07C57/42;C07C59/64;C07C59/68;C07C69/734;C07C231/02;C07C231/12;C07C231/18;C07C237/20;C07C247/12;C07D207/32;C07D207/33;C07D303/38;C07D303/40;C07D307/33;(IPC1-7):C07C231/02 |
主分类号 |
C07B61/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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