发明名称 |
Mammal 2P domain mechano-sensitive K<sup>+</sup> channel, cloning and applications thereof |
摘要 |
This invention relates to a protein including a mammalian K+ channel with two pore domains, designated TREK2, that produces currents whose current-voltage relationship is weakly inward rectifying in high symmetrical K+ conditions. This invention further relates to the isolation and characterization of such protein, as well as a method using TREK2 to identify bioactive compounds having anesthetic properties. |
申请公布号 |
AU7661001(A) |
申请公布日期 |
2002.01.08 |
申请号 |
AU20010076610 |
申请日期 |
2001.06.27 |
申请人 |
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE-CNRS |
发明人 |
MICHEL LAZDUNSKI;FLORIAN LESAGE;GEORGES ROMEY |
分类号 |
G01N33/50;A61K45/00;A61P23/00;C07K14/47;C07K14/705;C07K16/18;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/09;C12N15/12;C12P21/08;G01N33/15 |
主分类号 |
G01N33/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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